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RESEARCH BRIEF

Medications for Opioid Use Disorder

A plain-language guide to buprenorphine, methadone, naltrexone, access, safety, and continuity.

Medication access and retention are central evidence questions for opioid treatment comparisons.

Primary sources linkedEvidence separated from claimsUpdated September 2026
A patient discussing a treatment plan with a physician and nurse.
A patient discussing a treatment plan with a physician and nurse.
WHY THIS MATTERS

Buprenorphine, methadone, and naltrexone can treat opioid use disorder. The right option depends on the person, and stopping medication should be a clinical decision rather than a program rule.

THE EVIDENCE LENS

Read the claim and the source separately

Medication access and retention are central evidence questions for opioid treatment comparisons. Strong research identifies who produced the evidence, what population it covers, when it was updated, and what the source can actually support.

A precise source with acknowledged limits is more useful than a sweeping claim without a traceable basis.

PRACTICAL USE

Turn information into a safer next step

Clarify the need

Define the immediate medical, psychiatric, substance, medication, housing, and support concerns.

Verify the provider

Match the legal operator, location, authorized service, staffing, and advertised claim.

Confirm the pathway

Ask how assessment, treatment, medications, discharge, and aftercare connect.

Document the terms

Keep written benefit, price, exclusion, refund, and admission information.

PRIMARY STARTING SOURCES

Verify with authoritative records

FindTreatment.gov for treatment search, SAMHSA National Helpline for information, 988 Suicide and Crisis Lifeline for crisis support, and the relevant state licensing authority for current facility status. Call 911 for immediate danger or a medical emergency.